granulosa cell tumor การใช้

• AMH is also useful in diagnosing recurrence of granulosa cell tumors.
• A positive test for inhibin A and inhibin B can indicate a granulosa cell tumor.
• Deletions in the genes coding for SMAD1 and SMAD5 have also been linked to metastasic granulosa cell tumors in mice.
• It is found on the cell surface of Ewing's sarcoma tumors and is positive in granulosa cell tumors.
• Ollier disease and Maffucci syndrome are associated with granulosa cell tumors in children and may also be associated with Sertoli-Leydig tumors.
• Granulosa cell tumors of the ovary secrete AMH, and AMH testing has a sensitivity ranging between 76 and 93 % in diagnosing such tumors.
• Sex cord-stromal tumor, including estrogen-producing granulosa cell tumor, the benign thecoma, and virilizing Sertoli-Leydig cell tumor or arrhenoblastoma, accounts for 7 % of ovarian cancers.
• Other problems can include severe scoliosis ( twisting of the vertebrae ), limbal dermoids, and hearing loss ( see hearing loss with craniofacial syndromes ), and deafness or blindness in one or both ears / eyes, Granulosa cell tumors may be associated as well.